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Ajuga Δ24-Sterol Reductase Catalyzes the Direct Reductive Conversion of 24-Methylenecholesterol to Campesterol
Dimunito/Dwarf1 (DWF1) is an oxidoreductase enzyme that is responsible for the conversion of C(28)- and C(29)-Δ(24(28))-olefinic sterols to 24-methyl- and 24-ethylcholesterols. Generally, the reaction proceeds in two steps via the Δ(24(25)) intermediate. In this study, we characterized the ArDWF1 ge...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825020/ https://ncbi.nlm.nih.gov/pubmed/26872973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703470 |
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