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Approaches of targeting Rho GTPases in cancer drug discovery
INTRODUCTION: Rho GTPases are master regulators of actomyosin structure and dynamics and play pivotal roles in a variety of cellular processes including cell morphology, gene transcription, cell cycle progression and cell adhesion. Because aberrant Rho GTPase signaling activities are widely associat...
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| Udgivet i: | Expert Opin Drug Discov |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824952/ https://ncbi.nlm.nih.gov/pubmed/26087073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.2015.1058775 |
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