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TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model

Cyclosporine A (CsA) is widely used as an immunosuppressor in transplantation. Previous studies reported that CsA induces autophagy and that chronic treatment with CsA results in accumulation of autophagosomes and reduced autophagic clearance. Autophagy is a prosurvival process that promotes recover...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Yadav, Raj Kumar, Lee, Geum-Hwa, Lee, Hwa-Young, Li, Bo, Jung, Han-Eul, Rashid, Harun-Or, Choi, Min Kyung, Yadav, Binod Kumar, Kim, Woo-Ho, Kim, Kyung-Woon, Park, Byung-Hyun, Kim, Won, Lee, Yong-Chul, Kim, Hyung-Ryong, Chae, Han-Jung
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824609/
https://ncbi.nlm.nih.gov/pubmed/26305401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1082021
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