Chronic HMGCR/HMG-CoA reductase inhibitor treatment contributes to dysglycemia by upregulating hepatic gluconeogenesis through autophagy induction

Statins (HMGCR/HMG-CoA reductase [3-hydroxy-3-methylglutaryl-CoA reductase] inhibitors) are widely used to lower blood cholesterol levels but have been shown to increase the risk of type 2 diabetes mellitus. However, the molecular mechanism underlying diabetogenic effects remains to be elucidated. H...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Wang, Hye Jin, Park, Jae Yeo, Kwon, Obin, Choe, Eun Yeong, Kim, Chul Hoon, Hur, Kyu Yeon, Lee, Myung-Shik, Yun, Mijin, Cha, Bong Soo, Kim, Young-Bum, Lee, Hyangkyu, Kang, Eun Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824590/
https://ncbi.nlm.nih.gov/pubmed/26389569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1091139
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