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Variants in the HMG-CoA Reductase (HMGCR) Gene Influence Component Phenotypes in Polycystic Ovary Syndrome

OBJECTIVE: To study the role of genetic variation in the HMG-CoA reductase (HMGCR) gene in PCOS. DESIGN: Women with and without PCOS were genotyped for seven single nucleotide polymorphisms (SNPs) in HMGCR. SNPs and haplotypes were determined and tested for association with PCOS and its component tr...

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Bibliografiske detaljer
Main Authors: Xu, Ning, Taylor, Kent D., Azziz, Ricardo, Goodarzi, Mark O.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032056/
https://ncbi.nlm.nih.gov/pubmed/19327767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2009.01.158
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