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BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32

Although Atg32 is essential for mitophagy in yeast, no mammalian homolog has been identified. Here, we demonstrate that BCL2L13 (BCL2-like 13 [apoptosis facilitator]) is a functional mammalian homolog of Atg32. First, we hypothesized that a mammalian mitophagy receptor will share certain molecular f...

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Publicat a:Autophagy
Autors principals: Otsu, Kinya, Murakawa, Tomokazu, Yamaguchi, Osamu
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824574/
https://ncbi.nlm.nih.gov/pubmed/26506896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1084459
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