Leptin Production by Encapsulated Adipocytes Increases Brown Fat, Decreases Resistin, and Improves Glucose Intolerance in Obese Mice

The neuroendocrine effects of leptin on metabolism hold promise to be translated into a complementary therapy to traditional insulin therapy for diabetes and obesity. However, injections of leptin can provoke inflammation. We tested the effects of leptin, produced in the physiological adipocyte loca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: DiSilvestro, David J., Melgar-Bermudez, Emiliano, Yasmeen, Rumana, Fadda, Paolo, Lee, L. James, Kalyanasundaram, Anuradha, Gilor, Chen L., Ziouzenkova, Ouliana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824514/
https://ncbi.nlm.nih.gov/pubmed/27055280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153198
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