Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus

Genome-wide association studies (GWASs) have discovered numerous single nucleotide polymorphisms (SNPs) associated with human complex disorders. However, functional characterization of the disease-associated SNPs remains a formidable challenge. Here we explored regulatory mechanism of a SNP on chrom...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Nakaoka, Hirofumi, Gurumurthy, Aishwarya, Hayano, Takahide, Ahmadloo, Somayeh, Omer, Waleed H, Yoshihara, Kosuke, Yamamoto, Akihito, Kurose, Keisuke, Enomoto, Takayuki, Akira, Shigeo, Hosomichi, Kazuyoshi, Inoue, Ituro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824487/
https://ncbi.nlm.nih.gov/pubmed/27055116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005893
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