Molecular Characterization of an Intact p53 Pathway Subtype in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most aggressive histological type of epithelial ovarian cancer, which is characterized by a high frequency of somatic TP53 mutations. We performed exome analyses of tumors and matched normal tissues of 34 Japanese patients with HGSOC and observed a sub...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hayano, Takahide, Yokota, Yuki, Hosomichi, Kazuyoshi, Nakaoka, Hirofumi, Yoshihara, Kosuke, Adachi, Sosuke, Kashima, Katsunori, Tsuda, Hitoshi, Moriya, Takuya, Tanaka, Kenichi, Enomoto, Takayuki, Inoue, Ituro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252108/
https://ncbi.nlm.nih.gov/pubmed/25460179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114491
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