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RNA-binding Protein, GADD45-alpha, p27(Kip1), p53 and Genotoxic Stress Response in Relation to Chemoresistance in Cancer

Genotoxic chemotherapeutics particularly cisplatin remain effective for clinical management of various malignancies including lung cancer. However, the development of chemoresistance leads to treatment failure. The mechanisms by which tumor cells acquire resistance to chemotherapy are multifaceted i...

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Bibliografiske detaljer
Udgivet i:Mol Cell Pharmacol
Hovedforfatter: Sheikh, M. Saeed
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824310/
https://ncbi.nlm.nih.gov/pubmed/27066162
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