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Genetic Load of Loss-of-Function Polymorphic Variants in Great Apes

Loss of function (LoF) genetic variants are predicted to disrupt gene function, and are therefore expected to substantially reduce individual’s viability. Knowing the genetic burden of LoF variants in endangered species is of interest for a better understanding of the effects of declining population...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genome Biol Evol
Päätekijät: de Valles-Ibáñez, Guillem, Hernandez-Rodriguez, Jessica, Prado-Martinez, Javier, Luisi, Pierre, Marquès-Bonet, Tomàs, Casals, Ferran
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824148/
https://ncbi.nlm.nih.gov/pubmed/26912403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evw040
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