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TGF-β signaling in the kidney: profibrotic and protective effects

Transforming growth factor-β (TGF-β) is generally considered as a central mediator of fibrotic diseases. Indeed, much focus has been placed on inhibiting TGF-β and its downstream targets as ideal therapeutic strategies. However, pharmacological blockade of TGF-β has not yet translated into successfu...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Sureshbabu, Angara, Muhsin, Saif A., Choi, Mary E.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824143/
https://ncbi.nlm.nih.gov/pubmed/26739888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00365.2015
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