Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene

The transcription factor Nkx2.5 and the intermediate filament protein desmin are simultaneously expressed in cardiac progenitor cells during commitment of primitive mesoderm to the cardiomyogenic lineage. Up-regulation of Nkx2.5 expression by desmin suggests that desmin may contribute to cardiogenic...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Fuchs, Christiane, Gawlas, Sonja, Heher, Philipp, Nikouli, Sofia, Paar, Hannah, Ivankovic, Mario, Schultheis, Martina, Klammer, Julia, Gottschamel, Teresa, Capetanaki, Yassemi, Weitzer, Georg
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823984/
https://ncbi.nlm.nih.gov/pubmed/26787680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.014993
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