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Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy

One of the hallmarks of cardiomyopathy and heart failure is pronounced and progressive cardiomyocyte death. Understanding the mechanisms involved in cardiomyocyte cell death is a topic of great interest for treatment of cardiac disease. Mice null for desmin, the muscle-specific member of the interme...

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Detalhes bibliográficos
Main Authors: Weisleder, Noah, Taffet, George E., Capetanaki, Yassemi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321756/
https://ncbi.nlm.nih.gov/pubmed/14715896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0303202101
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