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Computing the origin and evolution of the ribosome from its structure — Uncovering processes of macromolecular accretion benefiting synthetic biology

Accretion occurs pervasively in nature at widely different timeframes. The process also manifests in the evolution of macromolecules. Here we review recent computational and structural biology studies of evolutionary accretion that make use of the ideographic (historical, retrodictive) and nomotheti...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Caetano-Anollés, Gustavo, Caetano-Anollés, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823900/
https://ncbi.nlm.nih.gov/pubmed/27096056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2015.07.003
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