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IL-Y, a Synthetic Member of the IL-12 Cytokine Family, Suppresses the Development of Type 1 Diabetes in NOD Mice

The IL-12 family of heterodimeric cytokines, consisting of IL-12, IL-23, IL-27, and IL-35, has important roles in regulating the immune response. IL-12 family members are comprised of a heterodimer consisting of α and β chains: IL-12 (p40 and p35), IL-23 (p40 and p19), IL-27 (Ebi3 and p28), and IL-3...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Flores, Rafael R., Kim, Eun, Zhou, Liqiao, Yang, Chenjie, Zhao, Jing, Gambotto, Andrea, Robbins, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823813/
https://ncbi.nlm.nih.gov/pubmed/26260044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445403
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