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Mutagenic specificities of four stereoisomeric benzo[c]phenanthrene dihydrodiol epoxides.

The pS189 shuttle vector carrying a supF target gene was used to compare the mutagenic specificities of the four configurational isomers of benzo[c]phenanthrene 3,4-dihydrodiol 1,2-epoxide. One of these isomers is the most tumorigenic dihydrodiol epoxide tested to date and another is essentially ina...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Bigger, C A, St John, J, Yagi, H, Jerina, D M, Dipple, A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729707/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.1.368
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