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Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

In eukaryotes, genomic DNA is compacted as chromatin, in which histones and DNA form the nucleosome as the basic unit. DMC1 and RAD51 are essential eukaryotic recombinases that mediate homologous chromosome pairing during homologous recombination. However, the means by which these two recombinases d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kobayashi, Wataru, Takaku, Motoki, Machida, Shinichi, Tachiwana, Hiroaki, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823753/
https://ncbi.nlm.nih.gov/pubmed/27052786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24228
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