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NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms

NDN is a maternally imprinted gene consistently expressed in normal ovarian epithelium, is dramatically downregulated in the majority of ovarian cancers. Little or no NDN expression could be detected in 73% of 351 epithelial ovarian cancers. NDN was also downregulated in 10 ovarian cancer cell lines...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Hailing, Das, Partha, Yu, Yinhua, Mao, Weiqun, Wang, Yan, Baggerly, Keith, Wang, Ying, Marquez, Rebecca T., Bedi, Anuja, Liu, Jinsong, Fishman, David, Lu, Zhen, Bast, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823087/
https://ncbi.nlm.nih.gov/pubmed/26689988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6576
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