Adoptive immunotherapy using T lymphocytes redirected to glypican-3 for the treatment of lung squamous cell carcinoma

There are unmet medical needs for patients with lung squamous cell carcinoma (LSCC). Therefore, in this study, we explored the antitumor potential of third-generation glypican 3 (GPC3)-redirected chimeric antigen receptor (CAR)-engineered T lymphocytes (CARgpc3 T cells) in tumor models of LSCC. Firs...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Kesang, Pan, Xiaorong, Bi, Yanyu, Xu, Wen, Chen, Cheng, Gao, Huiping, Shi, Bizhi, Jiang, Hua, Yang, Shengli, Jiang, Liyan, Li, Zonghai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823050/
https://ncbi.nlm.nih.gov/pubmed/26684028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6595
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