Adoptive immunotherapy using T lymphocytes redirected to glypican-3 for the treatment of lung squamous cell carcinoma

There are unmet medical needs for patients with lung squamous cell carcinoma (LSCC). Therefore, in this study, we explored the antitumor potential of third-generation glypican 3 (GPC3)-redirected chimeric antigen receptor (CAR)-engineered T lymphocytes (CARgpc3 T cells) in tumor models of LSCC. Firs...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Li, Kesang, Pan, Xiaorong, Bi, Yanyu, Xu, Wen, Chen, Cheng, Gao, Huiping, Shi, Bizhi, Jiang, Hua, Yang, Shengli, Jiang, Liyan, Li, Zonghai
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823050/
https://ncbi.nlm.nih.gov/pubmed/26684028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6595
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