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Crystal structure of a tankyrase 1–telomere repeat factor 1 complex
Telomere repeat factor 1 (TRF1) is a subunit of shelterin (also known as the telosome) and plays a critical role in inhibiting telomere elongation by telomerase. Tankyrase 1 (TNKS1) is a poly(ADP-ribose) polymerase that regulates the activity of TRF1 through poly(ADP-ribosyl)ation (PARylation). PARy...
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| Udgivet i: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822990/ https://ncbi.nlm.nih.gov/pubmed/27050267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16004131 |
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