The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells

OBJECTIVES: NSAIDs are used to relieve pain and decrease inflammation by inhibition of cyclooxygenase (COX)-catalyzed prostaglandin (PG) synthesis. PGs are fatty acid mediators involved in cartilage homeostasis, however the action of their synthesizing COX-enzymes in cartilage differentiation is not...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Caron, Marjolein M. J., Emans, Pieter J., Sanen, Kathleen, Surtel, Don A. M., Cremers, Andy, Ophelders, Daan, van Rhijn, Lodewijk W., Welting, Tim J. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822966/
https://ncbi.nlm.nih.gov/pubmed/27050768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153162
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