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Lysosomal Storage Diseases—Regulating Neurodegeneration

Autophagy is a complex pathway regulated by numerous signaling events that recycles macromolecules and can be perturbed in lysosomal storage diseases (LSDs). The concept of LSDs, which are characterized by aberrant, excessive storage of cellular material in lysosomes, developed following the discove...

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Detalhes bibliográficos
Publicado no:J Exp Neurosci
Main Authors: Onyenwoke, Rob U., Brenman, Jay E.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822725/
https://ncbi.nlm.nih.gov/pubmed/27081317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/JEN.S25475
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