Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases

Lysosomal storage disorders (LSDs) are inherited diseases characterized by lysosomal dysfunction and often showing a neurodegenerative course. There is no cure to treat the central nervous system in LSDs. Moreover, the mechanisms driving neuronal degeneration in these pathological conditions remain...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:EMBO Mol Med
Autores principales: Sambri, Irene, D'Alessio, Rosa, Ezhova, Yulia, Giuliano, Teresa, Sorrentino, Nicolina Cristina, Cacace, Vincenzo, De Risi, Maria, Cataldi, Mauro, Annunziato, Lucio, De Leonibus, Elvira, Fraldi, Alessandro
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210158/
https://ncbi.nlm.nih.gov/pubmed/27881461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606965
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares