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PhenomeExpress: A refined network analysis of expression datasets by inclusion of known disease phenotypes

We describe a new method, PhenomeExpress, for the analysis of transcriptomic datasets to identify pathogenic disease mechanisms. Our analysis method includes input from both protein-protein interaction and phenotype similarity networks. This introduces valuable information from disease relevant phen...

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Pubblicato in:Sci Rep
Autori principali: Soul, Jamie, Hardingham, Timothy E., Boot-Handford, Raymond P., Schwartz, Jean-Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822650/
https://ncbi.nlm.nih.gov/pubmed/25631385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08117
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