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Gene expression changes in damaged osteoarthritic cartilage identify a signature of non-chondrogenic and mechanical responses
OBJECTIVES: Joint degeneration in osteoarthritis (OA) is characterised by damage and loss of articular cartilage. The pattern of loss is consistent with damage occurring only where the mechanical loading is high. We have investigated using RNA-sequencing (RNA-seq) and systems analyses the changes th...
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| Publicado no: | Osteoarthritis Cartilage |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
W.B. Saunders For The Osteoarthritis Research Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4989048/ https://ncbi.nlm.nih.gov/pubmed/26973327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.03.007 |
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