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TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle

Transcription is an intrinsically dynamic process and requires the coordinated interplay of RNA polymerases (RNAPs) with nucleic acids and transcription factors. Classical structural biology techniques have revealed detailed snapshots of a subset of conformational states of the RNAP as they exist in...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Schulz, Sarah, Gietl, Andreas, Smollett, Katherine, Tinnefeld, Philip, Werner, Finn, Grohmann, Dina
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822635/
https://ncbi.nlm.nih.gov/pubmed/26979960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515817113
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