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Reevaluation of whether a soma–to–germ-line transformation extends lifespan in Caenorhabditis elegans

The germ lineage is considered to be immortal. In the quest to extend lifespan, a possible strategy is to drive germ-line traits in somatic cells, to try to confer some of the germ lineage’s immortality on the somatic body. Notably, a study in Caenorhabditis elegans suggested that expression of germ...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Knutson, Andrew Kekūpa'a, Rechtsteiner, Andreas, Strome, Susan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822628/
https://ncbi.nlm.nih.gov/pubmed/26976573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523402113
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