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Enantioselective Copper-Catalyzed Alkynylation of Benzopyranyl Oxo-carbenium Ions

We have developed highly enantioselective, copper-catalyzed alkynylations of benzopyranyl acetals. By using a copper(I) catalyst equipped with a chiral bis(oxazoline) ligand, high yields and enantioselectivities are achieved in the alkynylation of widely available, racemic isochroman and chromene ac...

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Foilsithe in:J Org Chem
Main Authors: Srinivas, Harathi D., Maity, Prantik, Yap, Glenn P. A., Watson, Mary P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822504/
https://ncbi.nlm.nih.gov/pubmed/25847687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b00364
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