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An intravaginal ring for the simultaneous delivery of an HIV-1 maturation inhibitor and reverse transcriptase inhibitor for prophylaxis of HIV transmission

Nucleocapsid 7 (NCp7) inhibitors have been investigated extensively for their role in impeding the function of HIV-1 replication machinery and their ability to directly inactivate the virus. A class of NCp7 zinc finger inhibitors, S-acyl-2-mercaptobenzamide thioesters (SAMTs), was investigated for t...

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Détails bibliographiques
Publié dans:J Pharm Sci
Auteurs principaux: Ugaonkar, Shweta R., Clark, Justin T., English, Lexie B., Johnson, Todd J., Buckheit, Karen W., Bahde, Robert J., Appella, Daniel H., Buckheit, Robert W., Kiser, Patrick F.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822498/
https://ncbi.nlm.nih.gov/pubmed/26149293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24551
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