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Novel ATRX gene damaging missense mutation c.6740A>C segregates with profound to severe intellectual deficiency without alpha thalassaemia

BACKGROUND & OBJECTIVES: ATRX is a recessive X-linked intellectual deficiency (X-LID) gene causing predominately alpha-thalassaemia with a wide and clinically heterogeneous spectrum of intellectual deficiency syndromes. Although alpha-thalassaemia is commonly present, some patients do not expres...

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Bibliografski detalji
Izdano u:Indian J Med Res
Glavni autori: Bouazzi, Habib, Thakur, Seema, Trujillo, Carlos, Alwasiyah, Mohammad Khalid, Munnich, Arnold
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822368/
https://ncbi.nlm.nih.gov/pubmed/26997013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5916.178589
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