αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition

Subretinal fibrosis is an end stage of neovascular age-related macular degeneration, characterized by fibrous membrane formation after choroidal neovascularization. An initial step of the pathogenesis is an epithelial-mesenchymal transition (EMT) of retinal pigment epithelium cells. αB-crystallin pl...

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Dades bibliogràfiques
Publicat a:Am J Pathol
Autors principals: Ishikawa, Keijiro, Sreekumar, Parameswaran G., Spee, Christine, Nazari, Hossein, Zhu, Danhong, Kannan, Ram, Hinton, David R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2016
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822331/
https://ncbi.nlm.nih.gov/pubmed/26878210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.11.014
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