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Dimension reduction and shrinkage methods for high dimensional disease risk scores in historical data
BACKGROUND: Multivariable confounder adjustment in comparative studies of newly marketed drugs can be limited by small numbers of exposed patients and even fewer outcomes. Disease risk scores (DRSs) developed in historical comparator drug users before the new drug entered the market may improve adju...
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| Publicado no: | Emerg Themes Epidemiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822311/ https://ncbi.nlm.nih.gov/pubmed/27053942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12982-016-0047-x |
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