Shared genetic control of expression and methylation in peripheral blood

BACKGROUND: Expression QTLs and epigenetic marks are often employed to provide an insight into the possible biological mechanisms behind GWAS hits. A substantial proportion of the variation in gene expression and DNA methylation is known to be under genetic control. We address the proportion of gene...

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Udgivet i:BMC Genomics
Main Authors: Shakhbazov, Konstantin, Powell, Joseph E., Hemani, Gibran, Henders, Anjali K., Martin, Nicholas G., Visscher, Peter M., Montgomery, Grant W., McRae, Allan F.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822256/
https://ncbi.nlm.nih.gov/pubmed/27048375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2498-4
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