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Keeping homologous recombination in check

Pathway choice is a critical event in the repair of DNA double-strand breaks. In a recent paper published in Nature, Orthwein et al. define a mechanism by which homologous recombination is controlled in G1 cells to favor non-homologous end joining.

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Fugger, Kasper, West, Stephen C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822126/
https://ncbi.nlm.nih.gov/pubmed/26902288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.25
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