FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

The mechanisms that allow breast cancer (BCa) cells to metabolically sustain rapid growth are poorly understood. Here we report that BCa cells are dependent on a mechanism to supply precursors for intracellular lipid production derived from extracellular sources and that the endothelial lipase (LIPG...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Slebe, Felipe, Rojo, Federico, Vinaixa, Maria, García-Rocha, Mar, Testoni, Giorgia, Guiu, Marc, Planet, Evarist, Samino, Sara, Arenas, Enrique J., Beltran, Antoni, Rovira, Ana, Lluch, Ana, Salvatella, Xavier, Yanes, Oscar, Albanell, Joan, Guinovart, Joan J., Gomis, Roger R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822041/
https://ncbi.nlm.nih.gov/pubmed/27045898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11199
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