FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

The mechanisms that allow breast cancer (BCa) cells to metabolically sustain rapid growth are poorly understood. Here we report that BCa cells are dependent on a mechanism to supply precursors for intracellular lipid production derived from extracellular sources and that the endothelial lipase (LIPG...

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Publicat a:Nat Commun
Autors principals: Slebe, Felipe, Rojo, Federico, Vinaixa, Maria, García-Rocha, Mar, Testoni, Giorgia, Guiu, Marc, Planet, Evarist, Samino, Sara, Arenas, Enrique J., Beltran, Antoni, Rovira, Ana, Lluch, Ana, Salvatella, Xavier, Yanes, Oscar, Albanell, Joan, Guinovart, Joan J., Gomis, Roger R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822041/
https://ncbi.nlm.nih.gov/pubmed/27045898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11199
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