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Conformational heterogeneity of the calmodulin binding interface
Calmodulin (CaM) is a ubiquitous Ca(2+) sensor and a crucial signalling hub in many pathways aberrantly activated in disease. However, the mechanistic basis of its ability to bind diverse signalling molecules including G-protein-coupled receptors, ion channels and kinases remains poorly understood....
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4822001/ https://ncbi.nlm.nih.gov/pubmed/27040077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10910 |
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