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Conformational dynamics of calmodulin in complex with the calmodulin dependent kinase kinase α calmodulin-binding domain.

As the primary intracellular calcium sensor, calmodulin (CaM) regulates numerous and diverse proteins. Several mechanisms, including tissue specific expression, localization and sequestration, work in concert to limit the total number of available targets of calmodulin within a cell. While the free...

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Detalhes bibliográficos
Main Authors: Marlow, Michael S., Wand, A. Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561178/
https://ncbi.nlm.nih.gov/pubmed/16846216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060420m
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