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Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
During the process of reprogramming to induced pluripotent stem (iPS) cells, somatic cells switch from oxidative to glycolytic metabolism, a transition associated with profound mitochondrial reorganization. Neither the importance of mitochondrial remodelling for cell reprogramming, nor the molecular...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821885/ https://ncbi.nlm.nih.gov/pubmed/27030341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11124 |
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