Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression

A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional changes associated with macrophage phenotype, but posttranscriptional control of...

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Veröffentlicht in:Nat Commun
Hauptverfasser: de Bruin, Ruben G., Shiue, Lily, Prins, Jurriën, de Boer, Hetty C., Singh, Anjana, Fagg, W. Samuel, van Gils, Janine M., Duijs, Jacques M. G. J., Katzman, Sol, Kraaijeveld, Adriaan O., Böhringer, Stefan, Leung, Wai Y., Kielbasa, Szymon M., Donahue, John P., van der Zande, Patrick H.J., Sijbom, Rick, van Alem, Carla M. A., Bot, Ilze, van Kooten, Cees, Jukema, J. Wouter, Van Esch, Hilde, Rabelink, Ton J., Kazan, Hilal, Biessen, Erik A. L., Ares Jr., Manuel, van Zonneveld, Anton Jan, van der Veer, Eric P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821877/
https://ncbi.nlm.nih.gov/pubmed/27029405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10846
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