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Nickel-Catalyzed Activation of Acyl C–O Bonds of Methyl Esters

We report the first catalytic method for activating the acyl C–O bonds of methyl esters through an oxidative addition process. The oxidative addition adducts, formed using nickel catalysis, undergo in situ trapping to provide anilide products. DFT calculations are used to support the proposed reacti...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Hie, Liana, Fine Nathel, Noah F., Hong, Xin, Yang, Yun-Fang, Houk, K. N., Garg, Neil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821830/
https://ncbi.nlm.nih.gov/pubmed/26804615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511486
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