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Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death

Despite immense interest in employing antimalarials as autophagy inhibitors to treat cancer, it remains unclear if these agents act predominantly via autophagy inhibition or whether other pathways direct their anti-cancer properties. By comparing the treatment effects of the antimalarials chloroquin...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Salas, Eduardo, Roy, Srirupa, Marsh, Timothy, Rubin, Brian, Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821829/
https://ncbi.nlm.nih.gov/pubmed/26434592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.348
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