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Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus
OBJECTIVES: CES1 encodes carboxylesterase-1, an important drug metabolizing enzyme with high expression in the liver. Previous studies have demonstrated a genomic translocation of the 5′ region from the poorly expressed pseudogene CES1P1, to CES1, yielding structural variant CES1VAR. The purpose of...
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| Vydáno v: | Pharmacogenet Genomics |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821783/ https://ncbi.nlm.nih.gov/pubmed/26871237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000206 |
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