Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Migration via Distinct and Overlapping Mechanisms

Osteoblast differentiation and migration are necessary for bone formation during bone remodeling. Mice lacking the proline-rich tyrosine kinase Pyk2 (Pyk2-KO) have increased bone mass, in part due to increased osteoblast proliferation. Megakaryocytes (MKs), the platelet-producing cells, also promote...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Eleniste, Pierre P., Patel, Vruti, Posritong, Sumana, Zero, Odette, Largura, Heather, Cheng, Ying-Hua, Himes, Evan R., Hamilton, Matthew, Baughman, Jenna, Kacena, Melissa A., Bruzzaniti, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821770/
https://ncbi.nlm.nih.gov/pubmed/26552846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25430
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