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Linoleic Acid Permeabilizes Gastric Epithelial Cells by Increasing Connexin43 Levels in the Cell Membrane Via a GPR40- and Akt-Dependent Mechanism

Linoleic acid (LA) is known to activate G-protein coupled receptors and connexin hemichannels (Cx HCs) but possible interlinks between these two responses remain unexplored. Here, we evaluated the mechanism of action of LA on the membrane permeability mediated by Cx HCs in MKN28 cells. These cells w...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Puebla, Carlos, Cisterna, Bruno A., Salas, Daniela P., Delgado-López, Fernando, Lampe, Paul D., Sáez, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821727/
https://ncbi.nlm.nih.gov/pubmed/26869446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2016.02.002
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