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Activation of Akt, Not Connexin 43 Protein Ubiquitination, Regulates Gap Junction Stability

The pore-forming gap junctional protein connexin 43 (Cx43) has a short (1–3 h) half-life in cells in tissue culture and in whole tissues. Although critical for cellular function in all tissues, the process of gap junction turnover is not well understood because treatment of cells with a proteasomal...

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Detalhes bibliográficos
Main Authors: Dunn, Clarence A., Su, Vivian, Lau, Alan. F., Lampe, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268419/
https://ncbi.nlm.nih.gov/pubmed/22139843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276261
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