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CLEC5A Mediates Macrophage Function and COPD Pathologies()

Chronic Obstructive Pulmonary Disease (COPD) is a devastating disease with no effective therapies. We investigated the role of the C-type lectin receptor, CLEC5A, in macrophage activation and pulmonary pathogenesis in a mouse model of COPD. We demonstrate that CLEC5A is expressed on alveolar macroph...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wortham, Brian W., Eppert, Bryan L., Flury, Jennifer L., Garcia, Sara Morgado, Donica, Walter R., Osterburg, Andrew, Joyce-Shaikh, Barbara, Cua, Daniel J., Borchers, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821706/
https://ncbi.nlm.nih.gov/pubmed/26927798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500978
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