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IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Group 2 innate lymphoid cells (ILC2) include IL-5– and IL-13–producing CRTh2(+)CD127(+) cells that are implicated in early protective immunity at mucosal surfaces. Whereas functional plasticity has been demonstrated for both human and mouse ILC3 subsets that can reversibly give rise to IFN-γ–produci...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Lim, Ai Ing, Menegatti, Silvia, Bustamante, Jacinta, Le Bourhis, Lionel, Allez, Matthieu, Rogge, Lars, Casanova, Jean-Laurent, Yssel, Hans, Di Santo, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821648/
https://ncbi.nlm.nih.gov/pubmed/26976630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151750
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